Story · Longevity & Aging · Sleep
The Vicious Cycle of Sleep Disruption and Inflammaging: Mechanisms, Consequences, and Therapeutic Opportunities
1 outlet · first reported by Aging Cell 6d ago
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6d ago
The Vicious Cycle of Sleep Disruption and Inflammaging: Mechanisms, Consequences, and Therapeutic OpportunitiesSleep disruption and circadian decline drive inflammaging and immune aging via the gut‐brain axis, NLRP3, and TLR4, forming a vicious cycle that accelerates cognitive decline and epigenetic aging. Targeting this sleep‐immune axis offers a viable strategy for promoting healthy longevity. ABSTRACT…
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