Role of Cdk5 in Mitochondrial Dysfunction: Phosphorylation of KANSL1 and Impairment of PINK1-Mediated Mitophagy

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1. 2d ago
   Research Square obscure study

   Role of Cdk5 in Mitochondrial Dysfunction: Phosphorylation of KANSL1 and Impairment of PINK1-Mediated Mitophagy

   Type 2 diabetes (T2D) is emerging as one of the most important risk factors for cognitive impairment and neurodegeneration, with mitochondrial dysfunction and defective mitophagy exacerbating disease progression. Despite the implication of aberrant cyclin-dependent kinase 5 (Cdk5) activation in…

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