A weight loss fibrotic response in visceral fat is driven by defective lysosome-dependent collagenolysis

Coverage, in order

1. 2d ago
   JCI Insight indie study

   A weight loss fibrotic response in visceral fat is driven by defective lysosome-dependent collagenolysis

   Obesity induces pathological remodeling of white adipose tissue (WAT), including chronic inflammation and fibrosis, which drive metabolic dysfunction. Although weight loss (WL) is the cornerstone of obesity treatment and improves systemic metabolic health, its effect on WAT remodeling remains…

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