Elucidating cancer cachexia–mediated aberrant cardiac wasting signaling in human iPSC-derived cardiac muscle

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1. 3d ago
   JCI Insight indie study

   Elucidating cancer cachexia–mediated aberrant cardiac wasting signaling in human iPSC-derived cardiac muscle

   Cancer cachexia is a debilitating syndrome of involuntary body mass loss featuring profound skeletal muscle wasting and high mortality. Cardiac muscle wasting is prominent in cancer patients and cancer survivors. We developed a human induced pluripotent stem cell–derived cardiac myocyte (hiPSC-CM)…

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