TLR5 signaling amplifies airway epithelial cell responses to influenza through a MyD88–JAK1 crosstalk

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1. 22h ago
   Research Square obscure study

   TLR5 signaling amplifies airway epithelial cell responses to influenza through a MyD88–JAK1 crosstalk

   Influenza vaccines and antivirals are compromised by viral evolution, underscoring the need for host-directed strategies that provide broad, strain-independent protection. While flagellin, a Toll-like receptor 5 (TLR5) agonist, has an established role in shielding against respiratory bacterial…

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