Lysergic Acid Diethylamide Induces Transcriptional Changes Opposing Signatures of Brain Ageing and Neurodegeneration

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   Aging Cell indie study in animals

   Lysergic Acid Diethylamide Induces Transcriptional Changes Opposing Signatures of Brain Ageing and Neurodegeneration

   Lysergic acid diethylamide (LSD) induces transcriptional programmes in the rodent prefrontal cortex that oppose signatures of human brain ageing and neurodegeneration. In primary cortical cultures, LSD also attenuates amyloid‐β‐induced alterations. Consistent with the signature reversion principle…

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