Fibroblast-enriched senescence-associated transcription and measurement-context-dependent FAP–matrix covariation in colorectal cancer

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   Research Square obscure study

   Fibroblast-enriched senescence-associated transcription and measurement-context-dependent FAP–matrix covariation in colorectal cancer

   Bulk tumour transcriptomes mix cellular composition, senescence-associated transcription and extracellular-matrix signals. We examined the compartmental distribution of senescence-associated transcription in colorectal cancer and its relationship to fibroblast activation protein (FAP)-linked matrix…

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