Story · Medicine & Biotech

Synergistic Effect of Akkermansia muciniphila and Bifidobacterium breve on Anti-Tumor Activity Through Targeted Suppression of the COX-2/PGE2 Axis

1 outlet · first reported by Research Square 23h ago

Coverage, in order

  1. 23h ago
    Research Square obscure study
    Synergistic Effect of Akkermansia muciniphila and Bifidobacterium breve on Anti-Tumor Activity Through Targeted Suppression of the COX-2/PGE2 Axis

    The gut microbiome critically modulates anti-tumor immunity, yet whether Akkermansia muciniphila (AKK) and Bifidobacterium breve (Bifido) act synergistically remains unknown. Here, we demonstrate that AKK monotherapy suppresses tumor growth in syngeneic murine colon cancer models while upregulating…

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