Bidirectional host–microbe signaling through cortisol metabolism by the gut bacterium Agathobaculum desmolans

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1. 15h ago
   Research Square obscure study

   Bidirectional host–microbe signaling through cortisol metabolism by the gut bacterium Agathobaculum desmolans

   Microbial endocrinology has developed principally around bacterial metabolism of catecholamines, yet the intestinal lumen receives far larger quantities of host steroids. Here we characterize cortisol metabolism by Agathobaculum desmolans ATCC 43058 as a model for the HPA axis arm of this…

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