Story · Longevity & Aging
Chemical crosslinking enables profiling of endogenous cell surface galectin-3 interactions
1 outlet · first reported by bioRxiv - Biochemistry 1d ago
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1d agoChemical crosslinking enables profiling of endogenous cell surface galectin-3 interactions
Galectin-3 is a {beta}-galactoside-binding lectin that organizes glycoproteins into cell surface lattices (multivalent interaction networks) that regulate biology spanning immune function, fibrosis, heart disease, and cancer progression. Galectin-3 engages promiscuous but low-affinity glycan…
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