Story · Longevity & Aging
Vaccination of pregnant mares with mRNA encoding a GPI-anchored form of the virulence-associated protein A of Rhodococcus equi induces strong IgG responses that are transferred to their foals
2 outlets · first reported by bioRxiv - Immunology 14d ago · latest 11d ago · 70 hours of coverage
Coverage, in order
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14d agoVaccination of pregnant mares with mRNA encoding a GPI-anchored form of the virulence-associated protein A of Rhodococcus equi induces strong IgG responses that are transferred to their foals
The bacterium Rhodococcus equi is a common cause of severe pneumonia in foals worldwide. Foals are exposed to R. equi from birth and are most susceptible in the first weeks of life. In North America, control measures are limited to transfusion to newborn foals of hyperimmune plasma whose potency is…
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13d agoVaccination targeting the novel endogenous tumor-associated antigen Gpr149 induces protective immunity against checkpoint inhibitor-refractory SB28 glioblastoma
Background: Glioblastoma is a lethal brain tumor notable for its limited spontaneous induction of CD8+ T cell responses. Vaccination may overcome this limitation by generating tumor-specific CD8+ T cells capable of mediating anti-tumor immunity in the brain. However, preclinical vaccine development…
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11d agoMaternal mRNA Vaccination: Evidence of Infant Protection, but Spike Protein and Long-Term Safety Questions Remain
Maternal mRNA Vaccination: Evidence of Infant Protection, but Spike Protein and Long-Term Safety Questions Remain
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