Story · Longevity & Aging

Oxidized EGCG redirects α-synuclein aggregation through shear-selected interactions

1 outlet · first reported by bioRxiv - Biochemistry 13d ago

Coverage, in order

  1. 13d ago
    bioRxiv - Biochemistry obscure study
    Oxidized EGCG redirects α-synuclein aggregation through shear-selected interactions

    -Synuclein (Syn) aggregation is central to Parkinson's disease pathology, and the green-tea polyphenol epigallocatechin gallate (EGCG) has been studied as an inhibit fibril formation. However, EGCG autoxidation and analyses under static, non-fibrillating conditions have obscured whether activity…

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