This cholesterol drug promised to be a game-changer. Why did it flop in the clinic — and is there still hope?

Coverage, in order

1. 9d ago
   Nature News indie study

   This cholesterol drug promised to be a game-changer. Why did it flop in the clinic — and is there still hope?

   Nature, Published online: 03 November 2026; doi:10.1038/d41586-026-03504-2 Physicians were excited about several therapies that slash levels of lipoprotein(a) — an important cardiovascular risk factor. One major trial failed to show a benefit, and now scientists are scrambling to work out what that…

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