Circadian feeding rhythm loss drives sex-specific β-cell dysfunction in diet-induced obesity

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1. 9d ago
   bioRxiv - Physiology obscure study

   Circadian feeding rhythm loss drives sex-specific β-cell dysfunction in diet-induced obesity

   Diet-induced obesity (DIO), modeled by a high-fat diet (HFD), adversely affects circadian glucose homeostasis partly by dysregulating fasting/feeding cycles. However, its impact on circadian {beta}-cell function and relevant transcriptional programs remains unclear. To investigate this, we exposed…

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