Cellular senescence

What it is

Cellular senescence is the state in which damaged or aged cells stop dividing but stay alive, secreting inflammatory signals that are thought to drive ageing and age-related disease. It is in the news because of senolytic drugs that aim to clear such cells, and research linking senescence to cancer therapy, heart ageing and metabolism. The biology is well established in animals; in people the evidence is early, with small trials of senolytics and no approved treatment. Supplements sold as senolytics are untested.

Written by the Alivewire editors from the coverage below, 1d ago. Not medical advice; how the ratings work.