Story · Mind & Brain · Nutrition

Chronic Sleep Disruption Activates the Transcriptional Unfolded Protein Response and Induces Compartment-Specific Proteomic Changes in Mice

1 outlet · first reported by bioRxiv - Neuroscience 8d ago

Coverage, in order

  1. 8d ago
    bioRxiv - Neuroscience obscure study observationalin animals
    Chronic Sleep Disruption Activates the Transcriptional Unfolded Protein Response and Induces Compartment-Specific Proteomic Changes in Mice

    Sleep disruption (SD) is associated with adverse brain health and increased risk of dementia, including Alzheimer's disease (AD), yet the pathological mechanisms underlying this association are not fully understood. Preclinical studies have shown that acute SD impairs cognition by altering…

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