Blood cell mitochondrial dysfunction as early indicator of alpha-synuclein pathology in rats

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1. 2d ago
   Research Square obscure study in animals

   Blood cell mitochondrial dysfunction as early indicator of alpha-synuclein pathology in rats

   Parkinson's disease (PD) is characterized by the progressive degeneration of dopaminergic neurons in the Substantia nigra pars compacta (SNpc) and the accumulation of α-synuclein (α-syn)-containing inclusions. Although the precise mechanisms underlying this process remain incompletely understood…

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