Story · Longevity & Aging · Sleep
Circadian Clock Coordination of the Notch-to-Wnt Signaling Switch Promotes Regenerative Myogenesis
1 outlet · first reported by bioRxiv - Cell Biology 4d ago
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4d agoCircadian Clock Coordination of the Notch-to-Wnt Signaling Switch Promotes Regenerative Myogenesis
Regenerative deficits of muscle stem cells (MuSCs) contribute to progressive muscle loss in muscular dystrophy. Successful regenerative repair requires a Notch to Wnt switch to allow MuSC expansion and myogenic differentiation, yet the underlying mechanisms remain poorly understood. Leveraging…
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