Story · Medicine & Biotech
Pharmacological enhancement of 20S proteasome-mediated degradation exposes a vulnerability in human papillomavirus (HPV)-driven cervical cancer
1 outlet · first reported by Research Square 3d ago
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3d agoPharmacological enhancement of 20S proteasome-mediated degradation exposes a vulnerability in human papillomavirus (HPV)-driven cervical cancer
Abstract: Despite the availability of prophylactic vaccines against human papillomavirus (HPV), infection and subsequent cervical cancer remain a significant global health problem. HPV viral oncoproteins E6 and E7 drive oncogenesis, in part through disruption of cell growth control pathways via…
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