Tau-vulnerable medial temporal lobe connectivity drives a functional-to-synaptic cascade in Alzheimer's disease

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1. 2d ago
   medRxiv (all subjects) obscure study

   Tau-vulnerable medial temporal lobe connectivity drives a functional-to-synaptic cascade in Alzheimer's disease

   Distinct tau-vulnerable and relatively spared subregions exist within the medial temporal lobe (MTL). However, it remains unclear that how functional connectivity (FC), anchored to tau-vulnerable MTL subregions, is related to tau pathology, synaptic dysfunction, and cognitive decline across the…

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