Preoperative SASP burden predicts perioperative vulnerability in older patients undergoing elective cardiac surgery: a prospective cohort study

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1. 6d ago
   GeroScience indie study observational

   Preoperative SASP burden predicts perioperative vulnerability in older patients undergoing elective cardiac surgery: a prospective cohort study

   Cellular senescence and its associated secretory phenotype (SASP) represent a fundamental mechanism of biological aging. SASP-related inflammation has been implicated in cardiovascular disease. However, its role in perioperative risk in cardiac surgery remains largely unexplored, and established…

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