Multi-omics analyses of HFpEF progression and regression reveals multi-organ-specific metabolic dysregulation and impaired inflammation resolution

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1. 3d ago
   Metabolism obscure study

   Multi-omics analyses of HFpEF progression and regression reveals multi-organ-specific metabolic dysregulation and impaired inflammation resolution

   Heart failure with preserved ejection fraction (HFpEF) is a complex cardiometabolic syndrome with limited effective therapies. Given its heterogeneity, whether withdrawal of cardiometabolic stress reverses HFpEF-associated inflammatory, metabolic, and molecular remodeling remains unclear.

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