Story · Medicine & Biotech · Mind & Brain

Genetic architecture and polygenic prediction of self-reported response to selective serotonin reuptake inhibitors in individuals with depression: a genome-wide meta-analysis

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Selective serotonin reuptake inhibitors (SSRIs) are first-line treatments for depression, but response is highly variable, and no robust genetic predictors have been identified. We conducted a genome-wide association meta-analysis of self-reported SSRI response in 62,879 individuals of European… (medRxiv (all subjects))

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  1. medRxiv (all subjects) obscure study meta-analysisn=62,879
    Genetic architecture and polygenic prediction of self-reported response to selective serotonin reuptake inhibitors in individuals with depression: a genome-wide meta-analysis

    Selective serotonin reuptake inhibitors (SSRIs) are first-line treatments for depression, but response is highly variable, and no robust genetic predictors have been identified. We conducted a genome-wide association meta-analysis of self-reported SSRI response in 62,879 individuals of European…

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