Depression

What it is

Depression is a persistent low mood and loss of interest that affects sleep, energy and concentration, and it is the leading cause of disability worldwide. Antidepressants and talking therapies work for many people but not all, which is why coverage has shifted toward new approaches: psychedelic-assisted therapy, ketamine, brain stimulation and anti-inflammatory angles. Social drivers such as discrimination, loneliness and financial stress show up in population studies as strongly as any biology.

This week · An oral LSD-based drug met its phase 3 endpoints in anxiety and depression, the furthest a classic psychedelic has reached in regulated trials.

Written by the Alivewire editors from the coverage below, 3d ago. Not medical advice; how the ratings work.