Dopamine turns mitochondrial stress into inflammation

Coverage, in order

1. 14d ago
   Cell Reports indie study

   Dopamine turns mitochondrial stress into inflammation

   Daniali et al. show that dopamine drives mitochondrial stress, mtDNA release, and cGAS–STING-dependent IL-6 production in human macrophages. These findings suggest a mechanism linking dopaminergic signaling to mtDNA damage signatures increasingly detected in blood from patients with Parkinson’s…

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