Nutrition · North America

Retatrutide Once Weekly in Adults with Knee Osteoarthritis Pain and Obesity

New England Journal of Medicine, Ahead of Print.

Study Confirms BMI Alone Can Miss Important Health Risks Associated with Obesity

A new approach to diagnosing obesity provides a more accurate picture of who faces serious health risks, and who may benefit from treatment, than body mass index (BMI) alone, according to an international study published in Nature .

New clinical definition versus BMI in diagnosing obesity

In 2025, the Lancet Diabetes & Endocrinology Commission proposed a new diagnostic framework for obesity that went beyond BMI alone to incorporate other metrics such as body fat distribution and organ function, and which distinguished between clinical and pre-clinical obesity. Some of the same…

Why the food industry opposes food ranking schemes: They work!

Julie Chapon of Yuka and Serge Hercberg of Nutri-Score sent me the link to their white paper written with Mathilde Touvier: Nutri-Score and Yuka : An Analysis of Lobbying Strategies to Undermine Consumer Information. The report cites seven strategies first used by the tobacco industry now used by…

VA trial to study effects of GLP-1s for alcohol use disorder among veterans

Dr. Chris Verrico discusses how GLP-1s show promise to treat alcohol use disorder among veterans and hopeful outcomes for the study.

Failure of Protein Quality Control Mechanisms in Muscle Aging

A cell is a bag of finely tuned molecular machinery moving at incredible speeds, pieces of that machinery ramming into one another countless times per second. Damage occurs constantly, a matter of inappropriate chemical reactions, broken proteins, misfolding of proteins, the machinery degraded and…

Calibrating Effects of a Novel Supplement Strategy on Vascular Measures of Aging

The supplement industry exists in its present vocal form because most people don't care about effect size at all. Or accuracy. Or truth. They hear that something has an effect, and run out to buy it. The industry marketing is tuned to take advantage of this aspect of human nature. But what are the…

expert reaction to study looking at energy density and levels of fat, sugar and salt in processed and ultra-processed food, and comparing existing and novel nutrient profiling models, as published in BMJ Medicine*

Scientists respond to study published in BMJ Medicine* looking at energy density and levels of fat, sugar and salt in processed and ultra-processed food, and comparing existing and novel nutrient profiling models. Prof Alberto Fiore, Professor in Food Chemistry and Technology, Abertay University…

Understanding the role of precision nutrition in dermatologic surgery

SAN DIEGO — Preprocedural nutritional assessments and changes may optimize dermatologic surgical outcomes for patients, according to a speaker at the American Society for Dermatologic Surgery Annual Meeting. Nutrition remains an underrecognized component of procedural optimization in dermatology…

Researchers find little if any progress toward reducing foodborne illness

A team of researchers from the FDA, CDC and USDA has found that the United States has made “none to very slight” progress toward foodborne illness reduction targets. The new study examined the Healthy People 2030 goals and found that there has actually been an increase incidence of infections from…

How the next Congress can fix our broken food system

Americans went to the polls this month with food issues top of mind. Rather than improve the food system, the last Congress and President Trump made matters worse by further fueling inflation, slashing federal feeding programs, and undermining food safety. Rising grocery store prices were a top…

Slow adoption: Only 15 of Africa’s 54 nations embrace genetic engineering food revolution. Here’s why

Genetically modified crops could help Africa feed its fast-growing population, but only 15 of the continent’s 54 nations have taken the plunge by running field trials or approving GM products. That’s the takeaway from a new review highlighted by Bioengineer, which pins the slow uptake largely on…

When your gut bacteria run out of fiber, they may start eating your gut lining

Scientists have discovered that gut bacteria can feed on the protective mucus lining your intestines, producing potentially harmful compounds, but fiber helps keep this activity in check. Overlooked proteins in plant foods also help shift gut bacteria toward producing beneficial substances…

Time to eat school lunch associated with increased meal consumption among elementary school students in a cross-sectional multi-state study

School nutrition policies related to lunch period lengths and free school meals have potential to improve children’s diets, but more research is needed to understand their impact.

Food avoidance, disordered eating behaviors, and eating disorders in inflammatory bowel disease: a systematic review of prevalence and associated factors

People living with inflammatory bowel disease (IBD) commonly modify their diet, but when restriction becomes persistent or rigid, it may reflect one of a spectrum of disordered eating behavior(s).

Creatine in 2026: 9 big takeaways from SupplySide Global

The supplement industry’s star ingredient is getting rebranded, reformulated and put behind lock and key. Here are the big innovations and hard questions about creatine.

A Clinical Trial Found That a Combination of Omega-3 Fatty Acids and Low-Dose Aspirin Had Results Comparable to Antibiotic Therapy

Key Findings from the Study Comparable Results: About 57.7% to 58% of patients receiving the omega-3 and aspirin combination achieved the main clinical treatment goal (having no more than four remaining deep periodontal pockets), which was nearly identical to the 58% to 59% success rate seen with…

A Supplement Kills Senescent Cells and Extends Life in Mice

A new study shows healthspan and lifespan increases in male mice following late-life treatment with vanadyl sulfate, a food-derived molecule marketed as an over-the-counter supplement [1]. Searching for vulnerabilities Cellular Senescence As your body ages, more of your cells become senescent…

HEPA Filters for Blood Sugar; ECMO-Equipped EMS & CPR; Valve-in-Valve-in-Valve TAVR

(MedPage Today) -- A sham-controlled trial showed that sleeping while using high‑efficiency particulate air (HEPA) filters in the bedroom improved blood sugar control, as highlighted by NYU Langone Health. A smartwatch artificial intelligence...

Aberdeen scholar's research on generative AI cited in landmark CJEU proceedings

Research by Dr Michiel Poesen has been cited in proceedings before the Court of Justice of the European Union (CJEU) as the Court considers legal questions arising from generative artificial intelligence.

Congratulations Berkeley: 76% of voters approve soda tax!

Me with Anna Lappé at a Yes on AA fundraiser in Berkeley October 14. Let’s start this week with some good news: Berkeley voters passed a higher soda tax by a vote of 76%. According to the press release , Berkeley voters reaffirmed their commitment to community health by approving Measure AA…

Women who use social media more are more open to “sugar relationships,” especially in looser cultures

Women who spend more time on social media tend to report a greater willingness to consider “sugar relationships,” a form of dating where companionship or intimacy is exchanged for financial or material support. According to a cross-national study of more than 22,000 women published in Archives of…

C Vitamini, D Vitamini ve Çinko Takviyeleri Kış Enfeksiyonlarından Koruyor mu? Bilimsel Araştırmalar Ne Söylüyor?

Bilimsel araştırmalar, kış aylarında sıkça başvurulan C vitamini, D vitamini ve çinko takviyelerinin soğuk algınlığını önlemede sınırlı etkiye sahip olduğunu gösteriyor.

Study Suggests Diet-Gut Microbe Interactions May Enhance Cancer Immunotherapy Response in Mice

As reported on Science Daily, a new preclinical study has revealed an unexpected link between nutrition and cancer treatment, with researchers finding that some diets commonly associated with weight gain appeared to improve the effectiveness of immunotherapy in mice. The findings highlight the…

Joyful Family Nutrition

Joyful Family Nutrition Anonymous (not verified) Tue, 11/10/2026 - 12:04 Program Name Joyful Family Nutrition Accepting Referrals from RH 0 Address 5775 Lemon Hill Ave Sacramento , CA 95824 United States Geocoding Field POINT (-121.439176 38.515938) Phone (857) 366-6175 Program Type CDC Record Type…

Aberdeen Law academic delivers opening plenary statement at COP31

Dr Mitchell Lennan, Lecturer in Environmental Law at the University of Aberdeen School of Law, delivered the opening plenary statement on behalf of the Research and Independent Non-Governmental Organizations (RINGO) constituency at the United Nations Climate Change Conference (COP31) in Antalya…

Orforglipron Cuts Sleep Apnea Burden by About Half

Obstructive sleep apnea (OSA) is another important complication of obesity that responds to treatment with incretin-based medicines. New research in JAMA provides compelling evidence that an oral GLP-1 medicine – orforglipron – can substantially improve this condition, even in people who are…

Nutritional risks of obesity-management medications

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America's School Lunch Loophole: Taxpayer Food, Corporate Profits—and the Fight Over What Children Eat

America's School Lunch Loophole: Taxpayer Food, Corporate Profits—and the Fight Over What Children Eat

Today I bought a supplement that contains GABA-5HTP-Magnesium Bisglycinate

I have delayed sleep phase disorder. I get sleepy later than normal, usually from 4 am onwards. Tomorrow or the day after, I'll start taking a supplement that contains these three elements. I'll tell you how it went in a few weeks. Whether it helped or not. submitted by /u/Wooden-Company391 [link]…

Judith Lacey Presents on the Safe Use of Supplements in Cancer Care at COSA 2026

Judith Lacey, Head of Supportive Care and integrative Oncology at Chris O’Brien Lifehouse, shared on LinkedIn: “An excellent first day at the COSA26 Annual Scientific Meeting! It was a pleasure

FDA moves to revoke permission for some chemicals used in food dyes

The FDA is revoking the authorization of certain substances used as additives in the production of color additives used in foods. With the revocations, the substances have no remaining uses as color additives in food or in the production of other color additives, according to the announcement from…

Biohacker influencers are claiming GLP-1 weight loss drugs extend lifespan. One mice experiment suggests there may be some truth to the claim

F ew drugs have been as disruptive to the field of medicine as glucagon-like peptide-1 (GLP-1) mimics. Based on a naturally occurring human peptide, synthetic analogs of GLP-1—including blockbuster drug semaglutide or Ozempic—have not only changed the way diabetes and weight loss are managed but…

Montenegro inches closer to EU membership with improved food safety

Montenegro has taken another step toward membership of the European Union by improving food safety. At a meeting in Brussels, officials from the EU and Montenegro agreed on progress made in two areas, including food safety, veterinary and phytosanitary policy.

4 Benefits of Shiitake Mushrooms You Should Know

Positive and Negative Aspects of Magnesium Supplementation

Positive and Negative Aspects of Magnesium Supplementation

Sustainable diets expert briefing

New briefing calls for nutrient density, affordability and accessibility to sit alongside environmental impact when assessing sustainable diets.

Mediterranean-style dietary components and self-reported depression: a cross-sectional analysis of 502,359 UK adults in the UK Biobank cohort

Background: Mediterranean-style diet adherence has been associated with lower depression prevalence, but studies are typically small and adjust for few confounders. We aimed to estimate cross-sectional associations between individual Mediterranean-style dietary components and reported depression…

Microglial, migrasomes promote high-fat diet-induced neurotoxicity

Systemic metabolic abnormalities are established drivers of cognitive decline, traditionally attributed to secondary sequelae of cerebrovascular dysfunction. However, cellular events linking early metabolic stress to subsequent neuronal injury and neurodegenerative processes remain poorly defined.

Longitudinal loss of skeletal muscle mass during systemic cancer treatment as prognostic indicator for overall survival: A systematic review and meta-analysis

Loss of skeletal muscle mass (SMM) during systemic anticancer treatment is common, but its prognostic significance across cancer types and treatment modalities has not been systematically quantified. This study aimed to review the literature and perform a meta-analysis exploring the association…

Inhibition of p38γ attenuates liver fibrosis progression by alleviating metabolic reprogramming

Liver fibrosis, a consequence of chronic liver disease, commonly advances to cirrhosis and HCC without intervention. P38γ, a member of the four p38 mitogen-activated protein kinases (p38 MAPKs) isoforms, was involved in inflammation across several diseases, yet its impact on the activation of…

Altered pre-supplementary motor area recruitment during semantic inhibition in individuals with elevated obsessive–compulsive traits

Background: Inhibitory control dysfunction has been implicated in obsessive–compulsive disorder (OCD), but neuroimaging research has focused predominantly on motor response inhibition. Whether obsessive–compulsive traits are associated with altered neural recruitment during semantic inhibition…

Obesity linked to up to 27% lower risk of death in dementia

A surprising study of more than 4,500 older adults found that people who were overweight or obese when diagnosed with dementia had a 16% to 27% lower risk of death than those at a normal weight. Researchers suspect that extra energy and muscle reserves may help patients survive the disease's toll…

6 Foods That Lower Blood Pressure Better Than Pomegranate Juice

4 Things That Can Happen to Your Body When You Take Vitamin D Every Day, According to Doctors

At the Helm of eHealth Exchange, Doug Dietzman Eyes New Use Cases for Data Sharing

Doug Dietzman, president and executive director of the eHealth Exchange, says payers haven't traditionally engaged in national interoperability, but that is about to change.

Early nutrition impacts later setmelanotide treatment of obesity in mice

A weight loss fibrotic response in visceral fat is driven by defective lysosome-dependent collagenolysis

Obesity induces pathological remodeling of white adipose tissue (WAT), including chronic inflammation and fibrosis, which drive metabolic dysfunction. Although weight loss (WL) is the cornerstone of obesity treatment and improves systemic metabolic health, its effect on WAT remodeling remains…

Mechanical forces enable human stem cell modeling of protein aggregation cardiomyopathy

Science Advances, Volume 12, Issue 46 , November 2026.

Diet Soda vs. Zero-Sugar Soda: Which Is Better for Blood Sugar?

Chia Pudding vs. Overnight Oats: Which Has More Protein?

Supplement industry faces new political terrain as Democrats take control of both Congress chambers

Karen Howard urges supplement leaders to trust the process, stay civically engaged and watch how the new legislative majority shapes industry regulation ahead.

Industry-funded studies of the week: peanuts and almonds

Nuts are a great snack but I am always skeptical when industry-funded studies find them to perform health miracles. Here are two parallel examples reported by SciTechDaily. I. Scientists Discover That Eating Peanuts Every Day May Help Protect the Aging Brain: Peanuts may offer more than a…

A high-fiber diet may clear away plastic in the gut

Research in mice shows that fiber may literally wrap around plastic particles to remove them from the gut.

Microbiome changes following immigration: Rethinking “Westernization” as an explanatory concept

Volume 18, Issue 1 , December 2026 .

Human cognitive performance-associated gut microbiota influences learning and memory in mice through arginine and pterin metabolism

Volume 18, Issue 1 , December 2026 .

Sarcopenic Obesity and Knee Osteoarthritis Pain

Mapping the genetic landscape of microbial lipid transformation in the intestinal microbiome

Volume 18, Issue 1 , December 2026 .

Lysergic Acid Diethylamide Induces Transcriptional Changes Opposing Signatures of Brain Ageing and Neurodegeneration

Lysergic acid diethylamide (LSD) induces transcriptional programmes in the rodent prefrontal cortex that oppose signatures of human brain ageing and neurodegeneration. In primary cortical cultures, LSD also attenuates amyloid‐β‐induced alterations. Consistent with the signature reversion principle…

Five Key Stories Taking Shape for OW2026

ObesityWeek 2026 promises to be the biggest yet, with more than a 175 scientific sessions, 700 research posters, and 5,000 researchers, clinicians, advocates, and policy leaders gathering November 14–17 at National Harbor outside Wa. The challenge will be deciding where to focus in this…

Neuronal injury and inflammatory protein signatures of postoperative delirium and cognitive decline in older adults—combining insights from post-surgical and memory clinic cohorts

Plasma proteomics may offer novel characterization of the longer-term inflammatory and neuronal injury alterations in older adults undergoing elective surgery, and their relations to delirium and cognitive decline. We leveraged plasma protein data from N = 616 participants across two longitudinal…

De novo design of ligases for programmable site-specific protein ubiquitylation

Protein ubiquitylation regulates numerous cellular processes, but difficulties in generating site-specifically ubiquitylated proteins limit our understanding of individual modification events. In cells, ubiquitylation is mediated by an E1-E2-E3 enzyme cascade, with substrate recognition largely…

Move over BMI: new obesity definition is better for predicting your health

Nature, Published online: 11 November 2026; doi:10.1038/d41586-026-03636-5 A fresh approach considers waist circumference, rather than just weight and height, providing a more accurate classification.

Proposed approach for diagnosing obesity outperforms old method

Nature, Published online: 11 November 2026; doi:10.1038/d41586-026-03425-0 A framework for diagnosing obesity that was proposed in 2025 incorporates waist circumference and related measures and distinguishes clinical from preclinical obesity on the basis of obesity-induced organ dysfunction. In an…

Validation of clinical and preclinical obesity across global cohorts

Nature, Published online: 11 November 2026; doi:10.1038/s41586-026-11237-5 A large-scale data analysis assesses the Lancet Commission’s proposed diagnostic framework for obesity, finding that this framework, in which BMI is combined with other criteria, such as waist circumference and organ…

A plant RNA-binding protein senses 2′,3′-cNMP produced by insect effectors

Nature, Published online: 11 November 2026; doi:10.1038/s41586-026-11259-z The rice RNA-binding protein NIB1 detects 2′,3′-cyclic nucleotide products from insect saliva RNase, forming nuclear condensates that recruit EDS1 to activate defence, revealing a conserved messenger-based immune pathway in…

Mitochondrial protein import defects enhance tumour immunogenicity

Nature, Published online: 11 November 2026; doi:10.1038/s41586-026-11249-1 Inhibition of mitochondrial protein import can enhance tumour immunogenicity by promoting mitochondrial DNA release.

Retraction Notice to: A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication

(Cell Reports 45, 116740; January 27, 2026)

Denaturation-sensitive BRET probes enable intracellular thermal shift measurements across diverse protein targets and biomolecular complexes

Thermal shift assays have revolutionized drug discovery, but can be limited in sensitivity and scalability. Combining the unique attributes of differential scanning fluorimetry (DSF) and cellular thermal shift (CETSA), we report the methodological framework for the bioluminescence resonance energy…

Communicating Nanoplastics, Obesity and Diabetes Risk – Interview with ECO2026 Prize Winner Pablo Jiménez López

Welcome, Pablo, and congratulations on receiving the ECO2026 Prize for Public Engagement & Science Communication in relation to your abstract “Ingestion of polystyrene nanoplastics promotes impaired glucose tolerance and fat accummulation in mice”. Could you tell us about yourself, and your work?…

18 Simple Plant-Based Swaps for Every Meal, According to Dietitians

Eating more plants can slash chronic disease risk and support day-to-day health for healthy aging.

Viewpoint: Bedeviled by “toxic inflammation”? How wellness grifters turn this scientific gray zone into a supplement jackpot

I n the wellness world, ‘inflammation’ has become the ultimate scapegoat for everything that ails the human body. But while immunology treats inflammation as a complex, dynamic spectrum, often essential for survival, wellness influencers treat it as a simple villain to be cleansed. That gap between…

What are the biochemical reasons for these effects of Vitamin c? Brain / hearth / histamine related.

Hello everyone. So I’ve been experimenting with vitamin c (bufferd) for a while now. Since then I’ve noticed a lot of effects that seem to be positive. I have more energy, less headache, no more dizziness, less hearth palpitations etc. I mainly take it for histamine issues/covid. Now on to the…

Experts urge caution over drug company campaigns to destigmatize obesity

We should be wary of campaigns by pharmaceutical companies to destigmatize obesity, say experts in The BMJ. Michael Viggars and colleagues argue that, while destigmatizing obesity is the right thing to do, there is a risk that companies profiting from obesity treatment come to influence public…

Glutathione + placenta + glynac supplements

So aside from wanting to look whiter and brighter, I've heard that these 3 are great for inflammation and for overall health. My dad and 3 of his siblings died from colon cancer, so ever since, I've always been health conscious. Now my sister just had her operation to have her colon removed…

Clinical trial explores potential brain health benefits of dietary supplement

A dietary supplement called urolithin A increased blood flow to the brain during mental activity in middle-aged adults with obesity, according to a University of Oklahoma study published in JAMA Network Open. The findings could help researchers better understand the relationship between the…

6 Drinks With More Sugar Than a Doughnut

Resistance exercise to attenuate lean mass loss during tirzepatide therapy for obesity: a randomized controlled trial

Nature Medicine, Published online: 09 November 2026; doi:10.1038/s41591-026-04752-5 Participants undergoing resistance exercise while receiving tirzepatide lost less lean mass than participants receiving tirzepatide alone.

The Effects of Vegetarian Diets on Blood Pressure: A Systematic Review and Meta-analysis of Randomized Clinical Trials

Hypertension is a global health issue, and a vegetarian diet has been represented as a key factor in blood pressure reduction by various observational studies and randomized clinical trials (RCTs).

DTC1225, a novel benzothiazole-based compound, ameliorates MASLD by restoring metabolic-redox homeostasis and promoting hepatic lipid remodeling

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a highly prevalent chronic liver disorder for which effective pharmacotherapies remain limited. Autophagy is a fundamental intracellular degradation and recycling process that maintains hepatic homeostasis by regulating lipid…