Resistance Training Molecular Signatures Identify Pharmacodynamic Biomarker Candidates in Duchenne Muscular Dystrophy

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1. 8h ago
   Research Square obscure study

   Resistance Training Molecular Signatures Identify Pharmacodynamic Biomarker Candidates in Duchenne Muscular Dystrophy

   Duchenne Muscular Dystrophy (DMD) is characterized by progressive skeletal muscle loss for which validated pharmacodynamic biomarkers remain a critical unmet need. Biomarker discovery in DMD is fundamentally constrained by small patient cohorts and the ethical limitations of repeated muscle biopsy…

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